Strategies to identify individuals with monogenic diabetes: results of an economic evaluation.

ABSTRACT:

Objectives

To evaluate and compare the lifetime costs associated with strategies to identify individuals with monogenic diabetes and change their treatment to more appropriate therapy.

Design

A decision analytical model from the perspective of the National Health Service (NHS) in England and Wales was developed and analysed. The model was informed by the literature, routinely collected data and a clinical study conducted in parallel with the modelling.

Setting

Secondary care in the UK.

Participants

Simulations based on characteristics of patients diagnosed with diabetes <30 years old.

Interventions

Four test-treatment strategies to identify individuals with monogenic diabetes in a prevalent cohort of diabetics diagnosed under the age of 30 years were mod

SUBMITTER: Peters JL 

PROVIDER: S-EPMC7150598 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature