No More Tears: Mining Sequencing Data for Novel Bt Cry Toxins with CryProcessor.

ABSTRACT: Bacillus thuringiensis (Bt) is a natural pathogen of insects and some other groups of invertebrates that produces three-domain Cry (3d-Cry) toxins, which are highly host-specific pesticidal proteins. These proteins represent the most commonly used bioinsecticides in the world and are used for commercial purposes on the market of insecticides, being convergent with the paradigm of sustainable growth and ecological development. Emerging resistance to known toxins in pests stresses the need to expand the list of known toxins to broaden the horizons of insecticidal approaches. For this purpose, we have elaborated a fast and user-friendly tool called CryProcessor, which allows productive and precise mining of 3d-Cry toxins. The only existing tool for mining Cry toxins, called a Bt

SUBMITTER: Shikov AE 

PROVIDER: S-EPMC7150774 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature