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Synthesis and Properties of Zinc-Modified Hydroxyapatite.


ABSTRACT: Hydroxyapatites modified with metal ions are the main inorganic components of bone tissue and are approved for use as components for biocomposites and coatings for surgical implants. This study examined prototypes of functional materials for bone implants based on hydroxyapatite modified with zinc ions. Zinc-modified hydroxyapatite was composed and synthesized. Using the XRD method, the phase composition was established. Using SEM, EPMA, and low-temperature nitrogen adsorption (BET) methods, surface properties were investigated. Antibacterial activity and biocompatibility have been established. The studied materials have antimicrobial activity; the samples did not cause significant changes in either the internal organs or the general condition of laboratory animals during the entire experiment.

SUBMITTER: Lytkina D 

PROVIDER: S-EPMC7151590 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature

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Synthesis and Properties of Zinc-Modified Hydroxyapatite.

Lytkina Daria D   Gutsalova Anastasiya A   Fedorishin Dmitriy D   Korotchenko Natalya N   Akhmedzhanov Rafik R   Kozik Vladimir V   Kurzina Irina I  

Journal of functional biomaterials 20200220 1


Hydroxyapatites modified with metal ions are the main inorganic components of bone tissue and are approved for use as components for biocomposites and coatings for surgical implants. This study examined prototypes of functional materials for bone implants based on hydroxyapatite modified with zinc ions. Zinc-modified hydroxyapatite was composed and synthesized. Using the XRD method, the phase composition was established. Using SEM, EPMA, and low-temperature nitrogen adsorption (BET) methods, sur  ...[more]

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