Noncoding RNAs Controlling Telomere Homeostasis in Senescence and Aging.
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ABSTRACT:
SUBMITTER: Rossi M
PROVIDER: S-EPMC7152597 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Publications
Noncoding RNAs Controlling Telomere Homeostasis in Senescence and Aging.
Rossi Martina M Gorospe Myriam M
Trends in molecular medicine 20200228 4
Aging is a universal and time-dependent biological decline associated with progressive deterioration of cells, tissues, and organs. Age-related decay can eventually lead to pathology such as cardiovascular and neurodegenerative diseases, cancer, and diabetes. A prominent molecular process underlying aging is the progressive shortening of telomeres, the structures that protect the ends of chromosomes, eventually triggering cellular senescence. Noncoding (nc)RNAs are emerging as major regulators o ...[more]
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