Clinical risk assessment model to predict venous thromboembolism risk after immobilization for lower-limb trauma.

ABSTRACT:

Background

Patients with lower-limb trauma requiring immobilization have an increased risk of venous thromboembolism (VTE). While thromboprophylaxis for all patients seems not effective, targeted thromboprophylaxis in high risk patients may be an appropriate alternative. Therefore, we aimed to develop and validate a risk assessment model for VTE risk: the TRiP(cast) score (Thrombosis Risk Prediction following cast immobilization).

Methods

In this prediction model study, for development, data were used from the MEGA study (case-control study into the etiology of VTE) and for validation, data from the POT-CAST trial (randomized trial on the effectiveness of thromboprophylaxis following cast immobilization) were used. Model discrimination was calculated by estimating the Area U

SUBMITTER: Nemeth B 

PROVIDER: S-EPMC7152815 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature