Porous Si Microparticles Infiltrated with Magnetic Nanospheres.

ABSTRACT: Porous silicon (pSi) microparticles obtained by porosification of crystalline silicon wafers have unique optical properties that, together with biodegradability, biocompatibility and absence of immunogenicity, are fundamental characteristics to candidate them as tracers in optical imaging techniques and as drug carriers. In this work, we focus on the possibility to track down the pSi microparticles also by MRI (magnetic resonance imaging), thus realizing a comprehensive tool for theranostic applications, i.e., the combination of therapy and diagnostics. We have developed and tested an easy, quick and low-cost protocol to infiltrate the COOH-functionalized pSi microparticles pores (tens of nanometers about) with magnetic nanospheres (SPIONs-Super Paramagnetic Iron Oxide Nanoparticles, about

SUBMITTER: Chiste E 

PROVIDER: S-EPMC7153621 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature