Ontology highlight
ABSTRACT:
SUBMITTER: Gerussi A
PROVIDER: S-EPMC7154090 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Gerussi Alessio A Lucà Martina M Cristoferi Laura L Ronca Vincenzo V Mancuso Clara C Milani Chiara C D'Amato Daphne D O'Donnell Sarah Elizabeth SE Carbone Marco M Invernizzi Pietro P
Frontiers in medicine 20200407
Primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC) are autoimmune cholangiopathies characterized by limited treatment options. A more accurate understanding of the several pathways involved in these diseases has fostered the development of novel and promising targeted drugs. For PBC, the characterization of the role of farnesoid X receptor (FXR) and perixosome-proliferator activated receptor (PPAR) has paved the way to several clinical trials including different molecules ...[more]