Impact of Positional Isomerism on Pathway Complexity in Aqueous Media.

ABSTRACT: Pathway complexity has become an important topic in recent years due to its relevance in the optimization of molecular assembly processes, which typically require precise sample preparation protocols. Alternatively, competing aggregation pathways can be controlled by molecular design, which primarily rely on geometrical changes of the building blocks. However, understanding how to control pathway complexity by molecular design remains elusive and new approaches are needed. Herein, we exploit positional isomerism as a new molecular design strategy for pathway control in aqueous self-assembly. We compare the self-assembly of two carboxyl-functionalized amphiphilic BODIPY dyes that solely differ in the relative position of functional groups. Placement of the carboxyl group at the 2-position e

SUBMITTER: Helmers I 

PROVIDER: S-EPMC7154731 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature