Demographic trends in the incidence of young-onset colorectal cancer: a population-based study.

ABSTRACT:

Background

Evidence is emerging that the incidence of colorectal cancer is increasing in young adults, but the descriptive epidemiology required to better understand these trends is currently lacking.

Methods

A population-based cohort study was carried out including all adults aged 20-49 years diagnosed with colorectal cancer in England between 1974 and 2015. Data were extracted from the National Cancer Registration and Analysis Service database using ICD-9/10 codes for colorectal cancer. Temporal trends in age-specific incidence rates according to sex, anatomical subsite, index of multiple deprivation quintile and geographical region were analysed using Joinpoint regression.

Results

A total of 56 134 new diagnoses of colorectal cancer were analysed. The most sustaine

SUBMITTER: Chambers AC 

PROVIDER: S-EPMC7155067 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature