Chronic sucralose consumption induces elevation of serum insulin in young healthy adults: a randomized, double blind, controlled trial.

ABSTRACT:

Background

Non-nutritive sweeteners (NNS) are widely consumed by humans due to their apparent innocuity, especially sucralose. However, several studies link sucralose consumption to weight gain and metabolic derangements, although data are still contradictory.

Objective

To determine the effect of acute and chronic consumption of sucralose on insulin and glucose profiles in young healthy adults.

Material and methods

This was a randomized, parallel, double-blind, placebo-controlled trial conducted in healthy young adults from 18 to 35 years old, without insulin resistance. A hundred thirty seven participants were randomized into three groups: a) volunteers receiving 48 mg sucralose, b) volunteers receiving 96 mg sucralose, and c) controls receiving water as placebo. All

SUBMITTER: Bueno-Hernandez N 

PROVIDER: S-EPMC7155288 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature