Prevalence and Impact of Underlying Diagnosis and Comorbidities on Chiari 1 Malformation.

ABSTRACT:

Background

Chiari malformation type 1 affects approximately one in 1,000 people symptomatically, although one in 100 meet radiological criteria, making it a common neurological disorder. The diagnosis of underlying conditions has become more sophisticated, and new radiological markers of disease have been described. We sought to determine the prevalence and impact of additional comorbidities and underlying diagnoses in patients with Chiari malformation type 1 on symptomatology and surgical treatment.

Methods

A retrospective review of 612 pediatric patients with a Chiari malformation type 1 diagnosis and imaging data evaluated between 2008 and 2018 was performed. Because of extensive clinical heterogeneity, patients were separated into four categories based on their primary c

SUBMITTER: Sadler B 

PROVIDER: S-EPMC7156318 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature