High-power light-emitting diode array design and assembly for practical photodynamic therapy research.

ABSTRACT:

Significance

Commercial lasers, lamps, and light-emitting diode (LED) light sources have stimulated the clinical translation of photodynamic therapy (PDT). Yet, the continued exploration of new photosensitizers (PSs) for PDT often requires separate activation wavelengths for each agent being investigated. Customized light sources for such research frequently come at significant financial or technical cost, especially when compounded over many agents and wavelengths.

Aim

LEDs offer potential as a cost-effective tool for new PS and multi-PS photodynamic research. A low-cost-per-wavelength tool leveraging high-power LEDs to facilitate efficient and versatile research is needed to further accelerate research in the field.

Approach

We developed and validated a high-power L

SUBMITTER: Kercher EM 

PROVIDER: S-EPMC7156854 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature