Viral metagenomic analysis of chickens with runting-stunting syndrome in the Republic of Korea.

ABSTRACT:

Background and aims

Runting-stunting syndrome (RSS) in chickens, also known as malabsorption syndrome, which is characterized by mild to severe enteritis and diagnosed through typical histopathologic examination as well as clinical signs, results in considerable economic losses. Despite the many studies carried out over decades to determine the etiologic agents of RSS involved in the disease, several outbreaks remained without the elucidation of, potentially multiple, etiologies involved.

Methods

We performed comparative analysis of viral metagenomes from four chicken flocks affected with RSS using next-generation sequencing. Primers for the detection of chicken enteric viruses were designed from the sequencing data obtained with metagenomics. Multiplex reverse transcription

SUBMITTER: Kim HR 

PROVIDER: S-EPMC7157833 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature