Reconstruction of a gene regulatory network of the induced systemic resistance defense response in Arabidopsis using boolean networks.

ABSTRACT: BACKGROUND:An important process for plant survival is the immune system. The induced systemic resistance (ISR) triggered by beneficial microbes is an important cost-effective defense mechanism by which plants are primed to an eventual pathogen attack. Defense mechanisms such as ISR depend on an accurate and context-specific regulation of gene expression. Interactions between genes and their products give rise to complex circuits known as gene regulatory networks (GRNs). Here, we explore the regulatory mechanism of the ISR defense response triggered by the beneficial bacterium Paraburkholderia phytofirmans PsJN in Arabidopsis thaliana plants infected with Pseudomonas syringae DC3000. To achieve this, a GRN underlying the ISR response was inferred using gene expression time-series data of ce

SUBMITTER: Timmermann T 

PROVIDER: S-EPMC7157984 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature