Characteristics of Clostridium difficile isolates and the burden of hospital-acquired Clostridium difficile infection in a tertiary teaching hospital in Chongqing, Southwest China.

ABSTRACT:

Background

Clostridium difficile infection (CDI), especially hospital-acquired Clostridium difficile infection (HA-CDI), continues to be a public health problem and has aroused great concern worldwide for years. This study aimed to elucidate the clinical and epidemiological features of HA-CDI and the characteristics of C.difficile isolates in Chongqing, Southwest China.

Methods

A case-control study was performed to identify the clinical incidence and risk factors of HA-CDI. C. difficile isolates were characterised by polymerase chain reaction (PCR) ribotyping, multilocus sequence typing (MLST), toxin gene detection and antimicrobial susceptibility testing.

Results

Of the 175 suspicious patients, a total of 122 patients with antibiotic-associated diarrhea (AAD) were in

SUBMITTER: Dai W 

PROVIDER: S-EPMC7157987 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature