Principal component analysis of adipocytokines and insulin associate with risk factors of cardiovascular diseases.

ABSTRACT:

Objectives

Obesity plays an important role in the development of chronic diseases like cardiovascular diseases and diabetes. The possible underlying mechanism for this connection is that adipose tissue secretes an array of chemical messenger adipokines proinflammatory cytokines (tumor necrosis factor-alpha, interleukin-6, and interleukin-1-beta). This study aimed to investigate the linkage between adipocytokines and insulin with the cardiovascular disease risk, with particular reference to the adipokines galectin-3, plasminogen activator inhibitor-1, and interleukin-1-beta, C-reactive protein, and monocyte chemoattractant protein.

Result

Two patterns were identified. The first pattern was galectin-3, plasminogen activator inhibitor-1 and interleukin-1-beta and the second one

SUBMITTER: Yarizadeh H 

PROVIDER: S-EPMC7157993 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature