Ethylene glycol and glycolic acid production from xylonic acid by Enterobacter cloacae.

ABSTRACT:

Background

Biological routes for ethylene glycol production have been developed in recent years by constructing the synthesis pathways in different microorganisms. However, no microorganisms have been reported yet to produce ethylene glycol naturally.

Results

Xylonic acid utilizing microorganisms were screened from natural environments, and an Enterobacter cloacae strain was isolated. The major metabolites of this strain were ethylene glycol and glycolic acid. However, the metabolites were switched to 2,3-butanediol, acetoin or acetic acid when this strain was cultured with other carbon sources. The metabolic pathway of ethylene glycol synthesis from xylonic acid in this bacterium was identified. Xylonic acid was converted to 2-dehydro-3-deoxy-D-pentonate catalyzed by D-xylo

SUBMITTER: Zhang Z 

PROVIDER: S-EPMC7158088 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature