Mortality and Morbidity in Kidney Transplant Recipients With a Failing Graft: A Matched Cohort Study.

ABSTRACT:

Background

Due to their history of renal disease and exposure to immunosuppression, kidney transplant recipients with a failing graft may be at higher risk of adverse outcomes compared to nontransplant controls. Understanding the burden of disease in transplant recipients may inform treatment decisions of people whose native kidneys are failing and may be eligible for a transplant.

Objective

To compare mortality and morbidity in kidney transplant recipients with a failing graft to matched nontransplant controls.

Design

Retrospective cohort study.

Setting

Alberta, Canada.

Patients

Kidney transplant recipients with a failing graft were identified as having at least 2 estimated glomerular filtration rate (eGFR) measurements between 15-30 mL/min/1.73 m²

SUBMITTER: Lam NN 

PROVIDER: S-EPMC7158256 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature