Scientific Review Committees as part of institutional review of human participant research: Initial implementation at institutions with Clinical and Translational Science Awards.

ABSTRACT:

Introduction

Scientific quality and feasibility are part of ethics review by Institutional Review Boards (IRBs). Scientific Review Committees (SRCs) were proposed to facilitate this assessment by the Clinical and Translational Science Award (CTSA) SRC Consensus Group. This study assessed SRC feasibility and impact at CTSA-affiliated academic health centers (AHCs).

Methods

SRC implementation at 10 AHCs was assessed pre/post-intervention using quantitative and qualitative methods. Pre-intervention, four AHCs had no SRC, and six had at least one SRC needing modifications to better align with Consensus Group recommendations.

Results

Facilitators of successful SRC implementation included broad-based communication, an external motivator, senior-level support, and committed

SUBMITTER: Selker HP 

PROVIDER: S-EPMC7159811 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature