Non-corticosteroid immunosuppressive medications for steroid-sensitive nephrotic syndrome in children.
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ABSTRACT:
SUBMITTER: Larkins NG
PROVIDER: S-EPMC7160055 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Publications
Non-corticosteroid immunosuppressive medications for steroid-sensitive nephrotic syndrome in children.
Larkins Nicholas G NG Liu Isaac D ID Willis Narelle S NS Craig Jonathan C JC Hodson Elisabeth M EM
The Cochrane database of systematic reviews 20200416
<h4>Background</h4>About 80% of children with steroid-sensitive nephrotic syndrome (SSNS) have relapses. Of these children, half relapse frequently, and are at risk of adverse effects from corticosteroids. While non-corticosteroid immunosuppressive medications prolong periods of remission, they have significant potential adverse effects. Currently, there is no consensus about the most appropriate second-line agent in children who are steroid sensitive, but who continue to relapse. In addition, t ...[more]
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