Diagnosis of deep vein thrombosis of the lower extremity: a systematic review and meta-analysis of test accuracy.

ABSTRACT: Deep vein thrombosis (DVT) of the lower extremities can be associated with significant morbidity and may progress to pulmonary embolism and postthrombotic syndrome. Early diagnosis and treatment are important to minimize the risk of these complications. We systematically reviewed the accuracy of diagnostic tests for first-episode and recurrent DVT of the lower extremities, including proximal compression ultrasonography (US), whole leg US, serial US, and high-sensitivity quantitative D-dimer assays. We searched Cochrane Central, MEDLINE, and EMBASE for eligible studies, reference lists of relevant reviews, registered trials, and relevant conference proceedings. Two investigators screened and abstracted data. Risk of bias was assessed using Quality Assessment of Diagnostic Accuracy Studies-2

SUBMITTER: Bhatt M 

PROVIDER: S-EPMC7160276 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature