Characteristics and outcomes of transitions among heart failure categories: a prospective observational cohort study.

ABSTRACT:

Aims

Patients with heart failure (HF) are typically designated as having reduced, mid-range, or preserved ejection fraction (EF) (HFrEF, HFmrEF, or HFpEF, respectively) because of the importance of left ventricular EF (LVEF) on therapeutic decisions and prognosis. However, such designations are not necessarily static, as there are many transitions among the three HF phenotypes during follow-up. This prospective longitudinal cohort study sought to examine the HF transitions over time and their clinical characteristics, prognosis, and response to medical therapy.

Methods and results

We identified 1920 patients from a prospective cohort with a primary diagnosis of HF between 1 January 2007 and 31 December 2012. The enrolled HF patients were re-classified into three groups on th

SUBMITTER: Gu J 

PROVIDER: S-EPMC7160467 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature