Relationship between B-type natriuretic peptide and invasive haemodynamics in patients with severe aortic valve stenosis.

ABSTRACT:

Aims

In patients with aortic stenosis (AS), B-type natriuretic peptide (BNP) is a prognostic marker. However, there is little information on the association between BNP and invasive haemodynamics in AS. The aim of the present study was to assess the hitherto not well-defined relationship between BNP and invasive haemodynamics in patients with severe AS undergoing aortic valve replacement (AVR) with a view to understand the link between high BNP and poor prognosis in these patients. In particular, we were interested in the association between BNP and combined pre-capillary and post-capillary pulmonary hypertension (CpcPH).

Methods and results

BNP was measured in 252 patients (age 74 ± 10 years, 58% male patients) with severe AS [indexed aortic valve area 0.4 ± 0.1 cm²

SUBMITTER: Maeder MT 

PROVIDER: S-EPMC7160488 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature