Incidence of end-stage renal disease after heart transplantation and effect of its treatment on survival.

ABSTRACT:

Aims

Many heart transplant recipients will develop end-stage renal disease in the post-operative course. The aim of this study was to identify the long-term incidence of end-stage renal disease, determine its risk factors, and investigate what subsequent therapy was associated with the best survival.

Methods and results

A retrospective, single-centre study was performed in all adult heart transplant patients from 1984 to 2016. Risk factors for end-stage renal disease were analysed by means of multivariable regression analysis and survival by means of Kaplan-Meier. Of 685 heart transplant recipients, 71 were excluded: 64 were under 18 years of age and seven were re-transplantations. During a median follow-up of 8.6 years, 121 (19.7%) patients developed end-stage renal disease

SUBMITTER: Roest S 

PROVIDER: S-EPMC7160492 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature