CYP1A2 genotype and acute effects of caffeine on resistance exercise, jumping, and sprinting performance.

ABSTRACT: BACKGROUND:It has been suggested that polymorphisms within CYP1A2 impact inter-individual variation in the response to caffeine. The purpose of this study was to explore the acute effects of caffeine on resistance exercise, jumping, and sprinting performance in a sample of resistance-trained men, and to examine the influence of genetic variation of CYP1A2 (rs762551) on the individual variation in responses to caffeine ingestion. METHODS:Twenty-two men were included as participants (AA homozygotes n = 13; C-allele carriers n = 9) and were tested after the ingestion of caffeine (3 mg/kg of body mass) and a placebo. Exercise performance was assessed with the following outcomes: (a) movement velocity and power output in the bench press exercise with loads of 25, 50, 75, and 90% of one-repetiti

SUBMITTER: Grgic J 

PROVIDER: S-EPMC7161272 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature