Advanced implantable drug delivery technologies: transforming the clinical landscape of therapeutics for chronic diseases.

ABSTRACT: Chronic diseases account for the majority of all deaths worldwide, and their prevalence is expected to escalate in the next 10 years. Because chronic disorders require long-term therapy, the healthcare system must address the needs of an increasing number of patients. The use of new drug administration routes, specifically implantable drug delivery devices, has the potential to reduce treatment-monitoring clinical visits and follow-ups with healthcare providers. Also, implantable drug delivery devices can be designed to maintain drug concentrations in the therapeutic window to achieve controlled, continuous release of therapeutics over extended periods, eliminating the risk of patient non-compliance to oral treatment. A higher local drug concentration can be achieved if the device is impla

SUBMITTER: Pons-Faudoa FP 

PROVIDER: S-EPMC7161312 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature