Estimation of Wave Condition Number From Pressure Waveform Alone and Its Changes With Advancing Age in Healthy Women and Men.

ABSTRACT:

Introduction

The wave condition number (WCN) is a non-dimensional number that determines the state of arterial wave reflections. WCN is equal to HR × L _eff /PWV where HR, L _eff , and PWV are the heart rate, effective length, and pulse wave velocity, respectively. It has been shown that a value of WCN = 0.1 indicates the optimum state of arterial wave reflection in which left ventricle workload is minimized. The pressure wave, flow wave, and PWV are all required to compute WCN, which may limit the potential clinical utility of WCN. The aims of this study are as follows: (1) to assess the feasibility of approximating WCN from the pressure waveform alone (WCN _Pinf ), and (2) to provide the proof-of-concept that WCN _Pinf

SUBMITTER: Pahlevan NM 

PROVIDER: S-EPMC7161432 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature