Initial Assessment of the Percutaneous Electrical Phrenic Nerve Stimulation System in Patients on Mechanical Ventilation.

ABSTRACT:

Objectives

Maintaining diaphragm work using electrical stimulation during mechanical ventilation has been proposed to attenuate ventilator-induced diaphragm dysfunction. This study assessed the safety and feasibility of temporary percutaneous electrical phrenic nerve stimulation on user-specified inspiratory breaths while on mechanical ventilation.

Design

Two-center, nonblinded, nonrandomized study.

Setting

Hospital ICU.

Patients

Twelve patients mechanically ventilated from 48 hours to an expected 7 days.

Interventions

Leads were inserted to lie close to the phrenic nerve in the neck region using ultrasound guidance. Two initial patients had left-sided placement only with remaining patients undergoing bilateral lead placement. Percutaneous electrical phr

SUBMITTER: O'Rourke J 

PROVIDER: S-EPMC7161723 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature