Hemoglobin and hepcidin have good validity and utility for diagnosing iron deficiency anemia among pregnant women.

ABSTRACT:

Background/objectives

Screening and diagnosis of iron deficiency anemia (IDA) is cumbersome as it may require testing for hemoglobin, ferritin, and an inflammatory biomarker. The aim of this study was to compare the diagnostic capacity of hematologic biomarkers to detect IDA among pregnant women in Tanzania.

Subjects/methods

We pooled data from an iron supplementation trial of 1500 iron-replete pregnant woman and a prospective cohort of 600 iron-deficient pregnant women. Receiver operating characteristic curves (ROC) for hematologic biomarkers were used to assess the sensitivity, specificity, and area under the curve (AUC) for iron deficiency (ID) and iron deficiency anemia (IDA), crude, or corrected for inflammation. Regression models assessed the relationship of baseline b

SUBMITTER: Abioye AI 

PROVIDER: S-EPMC7162716 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature