Nonlinear voxel-based finite element model for strength assessment of healthy and metastatic proximal femurs.

ABSTRACT: Nonlinear finite element (FE) models can accurately quantify bone strength in healthy and metastatic femurs. However, their use in clinical practice is limited since state-of-the-art implementations using tetrahedral meshes involve a lot of manual work for which specific modelling software and engineering knowledge are required. Voxel-based meshes could enable the transition since they are robust and can be highly automated. Therefore, the aim of this work was to bridge the modelling gap between the tetrahedral and voxel-based approach. Specifically, we validated a nonlinear voxel-based FE method relative to experimental data from 20 femurs with and without artificial metastases that had been mechanically loaded until failure. CT scans of the femurs were segmented and automatically convert

SUBMITTER: Sas A 

PROVIDER: S-EPMC7163060 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature