Effect of climatic factors on the seasonal fluctuation of human brucellosis in Yulin, northern China.

ABSTRACT: BACKGROUND:Brucellosis is a serious public health problem primarily affecting livestock workers. The strong seasonality of the disease indicates that climatic factors may play important roles in the transmission of the disease. However, the associations between climatic variability and human brucellosis are still poorly understood. METHODS:Data for a 14-year series of human brucellosis cases and seven climatic factors were collected in Yulin City from 2005 to 2018, one of the most endemic areas in northern China. Using cross-correlation analysis, the Granger causality test, and a distributed lag non-linear model (DLNM), we assessed the quantitative relationships and exposure-lag-response effects between monthly climatic factors and human brucellosis. RESULTS:A total of 7103 cases of human

SUBMITTER: Liu K 

PROVIDER: S-EPMC7164191 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature