Mapping lymphatic filariasis in Loa loa endemic health districts naive for ivermectin mass administration and situated in the forested zone of Cameroon.

ABSTRACT: BACKGROUND:The control of lymphatic filariasis (LF) caused by Wuchereria bancrofti in the Central African Region has been hampered by the presence of Loa loa due to severe adverse events that arise in the treatment with ivermectin. The immunochromatographic test (ICT) cards used for mapping LF demonstrated cross-reactivity with L. loa and posed the problem of delineating the LF map. To verify LF endemicity in forest areas of Cameroon where mass drug administration (MDA) has not been ongoing, we used the recently developed strategy that combined serology, microscopy and molecular techniques. METHODS:This study was carried out in 124 communities in 31 health districts (HDs) where L. loa is present. At least 125 persons per site were screened. Diurnal blood samples were investigated for circu

SUBMITTER: Beng AA 

PROVIDER: S-EPMC7164349 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature