Diagnostic value of the molecular detection of Sarcoptes scabiei from a skin scraping in patients with suspected scabies.

ABSTRACT: Scabies is a highly contagious parasitic disease associated with long-term residence in nursing homes, and it is a public health burden worldwide. However, atypical skin manifestations are frequent and the widely used diagnostic test based on microscopic examinations has limited sensitivity. We evaluated the diagnostic value of polymerase chain reaction (PCR) from skin scraping in patients with suspected scabies. Adult patients with suspected scabies, unrelated diseases or healthy volunteers were enrolled at a tertiary hospital, in Seoul, South Korea, from December 2017 through October 2018. We classified participants based on the consensus criteria established by the International Alliance for the Control of Scabies in 2018; confirmed (microscopic mite detection), clinical (scabies burrow

SUBMITTER: Bae M 

PROVIDER: S-EPMC7164670 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature