The role of microbes in the pathogenesis of acute rhinosinusitis in young adults.

ABSTRACT:

Objectives/hypothesis

To provide information on the course of acute rhinosinusitis (ARS) with sequential nasal and paranasal microbiological data and their correlation with clinical outcomes.

Study design

We conducted a prospective cohort study among 50 Finnish military recruits with clinically diagnosed ARS in spring 2012.

Methods

We collected symptom, nasal endoscopy, and cone-beam CT (CBCT) scores during the early (2-3 days from onset) and later phases (9-10 days). We took viral samples from the nasopharynx (multiplex respiratory virus polymerase chain reaction [PCR]), bacterial culture from the middle meatus during both phases, and both viral and bacterial samples from the maxillary sinus aspirate (respiratory virus PCR, bacterial culture, broad-range bacterial PC

SUBMITTER: Autio TJ 

PROVIDER: S-EPMC7165696 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature