A study of the probable transmission routes of MERS-CoV during the first hospital outbreak in the Republic of Korea.

ABSTRACT: Infections caused by the Middle East respiratory syndrome coronavirus (MERS-CoV) are a serious health issue due to their prevalence and associated mortality. However, the transmission routes of the virus remain unclear, and thus, the current recommended control strategies are not evidence based. In this study, we investigated the transmission routes of MERS-CoV during the first nosocomial outbreak in the Republic of Korea in May 2015 using a multi-agent modeling framework. We identified seven hypothesized transmission modes based on the three main transmission routes (long-range airborne, close contact, and fomite). The infection risks for each hypothesis were estimated using the multi-agent modeling framework. Least-squares fitting was conducted to compare the distribution of the predicte

SUBMITTER: Xiao S 

PROVIDER: S-EPMC7165997 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature