HPV prevalence around the time of sexual debut in adolescent girls in Tanzania.

ABSTRACT:

Objectives

Cervical cancer is the leading cause of cancer-related mortality among women in sub-Saharan Africa (SSA). Data on human papillomavirus (HPV) epidemiology in adolescent girls in SSA are essential to inform HPV vaccine policy recommendations for cervical cancer prevention. We assessed the burden of HPV infection, and risk factors for infection, among adolescent girls around the time of sexual debut.

Methods

Cross-sectional study of secondary school girls aged 17-18 years in Tanzania. Consenting participants provided samples for HPV and STI testing. Vaginal swabs were tested for 37 HPV genotypes by Roche Linear Array. Logistic regression was used to identify factors associated with HPV infection. Y chromosome was tested as a marker of recent condomless sex.

Result

SUBMITTER: Baisley KJ 

PROVIDER: S-EPMC7167299 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature