Long-term morbidity of respiratory viral infections during chemotherapy in children with leukaemia.

ABSTRACT:

Background

Respiratory viruses are a common cause of infection in immunosuppressed children undergoing cancer therapy. Pulmonary sequelae have been documented following respiratory viral infections (RVIs) in hematopoietic stem cell transplant (HSCT) recipients; however potential late effects in children undergoing nonmyeloablative chemotherapy have not been investigated.

Aim

To evaluate the long-term pulmonary morbidity of respiratory viral infections during chemotherapy in children with acute lymphoblastic leukemia (ALL).

Methods

Childhood ALL survivors, aged 7 to 18 years, greater than 6 months posttreatment were recruited. Exclusion criteria included HSCT or proven bacterial/fungal respiratory infection during treatment. Subjects were classified into "viral" or "co

SUBMITTER: Lin B 

PROVIDER: S-EPMC7167615 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature