Transforming growth factor-beta 1 in humidifier disinfectant-associated children's interstitial lung disease.

ABSTRACT:

Background

Humidifier disinfectant-associated children's interstitial lung disease has an unpredictable clinical course with a high morbidity and mortality.

Objectives

To evaluate the differences in clinical findings between survivors and non-survivors of humidifier disinfectant-associated children's interstitial lung disease. To evaluate dynamic changes in serum cytokines related to inflammation and fibrosis in lung injury, and to determine whether these changes are predictive of survival in this disease.

Methods

We evaluated 17 children with humidifier disinfectant-associated children's interstitial lung disease, from whom serum samples were obtained weekly during hospitalization. The severity of chest tomographic and lung pathologic findings was scored. Levels of s

SUBMITTER: Kim YH 

PROVIDER: S-EPMC7167780 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature