Ontology highlight
ABSTRACT:
SUBMITTER: Ishchuk OP
PROVIDER: S-EPMC7167926 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Ishchuk Olena P OP Sterner Olov O Ellervik Ulf U Manner Sophie S
Antibiotics (Basel, Switzerland) 20191230 1
The opportunistic human fungal pathogen <i>Candida albicans</i> relies on cell morphological transitions to develop biofilm and invade the host. In the current study, we developed new regulatory molecules, which inhibit the morphological transition of <i>C. albicans</i> from yeast-form cells to cells forming hyphae. These compounds, benzyl α-l-fucopyranoside and benzyl β-d-xylopyranoside, inhibit the hyphae formation and adhesion of <i>C. albicans</i> to a polystyrene surface, resulting in a red ...[more]