2-deoxy-d-glucose Ameliorates Animal Models of Dermatitis.
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ABSTRACT:
SUBMITTER: Choi SY
PROVIDER: S-EPMC7167934 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Publications
2-deoxy-d-glucose Ameliorates Animal Models of Dermatitis.
Choi Soo Young SY Heo Min-Jeong MJ Lee Chanmi C Choi Yeong Min YM An In-Sook IS Bae Seunghee S An Sungkwan S Jung Jin Hyuk JH
Biomedicines 20200124 2
Glucose metabolism is a key metabolic pathway that orchestrates cellular homeostasis by generating ATP, nucleotides, and amino acids. Abnormal glucose signaling has been found in many diseases including cancers and inflammatory diseases. According to recent report, glycolysis contributes to pathogenesis of psoriasis and ablation of Glut1 attenuates animal models of psoriasis. While we were screening a molecular target for atopic dermatitis, we found the levels of glucose transporters including G ...[more]
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