Differential expression of serum/plasma proteins in various infectious diseases: specific or nonspecific signatures.

ABSTRACT: Apart from direct detection of the infecting organisms or biomarker of the pathogen itself, surrogate host markers are also useful for sensitive and early diagnosis of pathogenic infections. Early detection of pathogenic infections, discrimination among closely related diseases with overlapping clinical manifestations, and monitoring of disease progression can be achieved by analyzing blood biomarkers. Therefore, over the last decade large numbers of proteomics studies have been conducted to identify differentially expressed human serum/plasma proteins in different infectious diseases with the intent of discovering novel potential diagnostic/prognostic biomarkers. However, in-depth review of the literature indicates that many reported biomarkers are altered in the same way in multiple infe

SUBMITTER: Ray S 

PROVIDER: S-EPMC7168033 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature