Allergic sensitization is associated with rhinovirus-, but not other virus-, induced wheezing in children.

ABSTRACT:

Background

Data on the link between atopy and viral wheeze are limited.

Aim

To evaluate the association between IgE sensitization and viral infection in wheezing children.

Methods

This is an observational study in hospitalized wheezing children (n = 247; median age 1.6 ; interquartile range 1.1, 2.9). Eighteen respiratory viral infections were studied using all available methods. A specific immunoglobulin E (IgE) sensitization for common food and aeroallergens and other atopy-related variables including total IgE, blood and nasal eosinophils, exhaled nitric oxide, eczema and atopic eczema, parental allergy and asthma, number of wheezing episodes, positive asthma predictive index or asthma and use of inhaled corticosteroid were correlated with specific viral etiology.<

SUBMITTER: Jartti T 

PROVIDER: S-EPMC7168081 | biostudies-literature | 2010 Nov

REPOSITORIES: biostudies-literature