Campylobacter jejuni and Campylobacter coli autotransporter genes exhibit lineage-associated distribution and decay.

ABSTRACT:

Background

Campylobacter jejuni and Campylobacter coli are major global causes of bacterial gastroenteritis. Whilst several individual colonisation and virulence factors have been identified, our understanding of their role in the transmission, pathogenesis and ecology of Campylobacter has been hampered by the genotypic and phenotypic diversity within C. jejuni and C. coli. Autotransporter proteins are a family of outer membrane or secreted proteins in Gram-negative bacteria such as Campylobacter, which are associated with virulence functions. In this study we have examined the distribution and predicted functionality of the previously described capC and the newly identified, related capD autotransporter gene families in Campylobacter.

Results

Two capC-like autotransporter f

SUBMITTER: Mehat JW 

PROVIDER: S-EPMC7168839 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature