Clinical outcomes of current medical approaches for Middle East respiratory syndrome: A systematic review and meta-analysis.

ABSTRACT: Middle East respiratory syndrome (MERS) is a respiratory disease caused by MERS coronavirus. Because of lack of vaccination, various studies investigated the therapeutic efficacy of antiviral drugs and supportive remedies. A systematic literature search from 10 databases was conducted and screened for relevant articles. Studies reporting information about the treatment of MERS coronavirus infection were extracted and analyzed. Despite receiving treatment with ribavirin plus IFN, the case fatality rate was as high as 71% in the IFN-treatment group and exactly the same in patients who received supportive treatment only. Having chronic renal disease, diabetes mellitus and hypertension increased the risk of mortality (P < .05), and chronic renal disease is the best parameter to predict the mor

SUBMITTER: Morra ME 

PROVIDER: S-EPMC7169085 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature