Critical review and uncertainty analysis of factors influencing influenza transmission.

ABSTRACT: Influenza remains a significant threat to public health, yet there is significant uncertainty about the routes of influenza transmission from an infectious source through the environment to a receptor, and their relative risks. Herein, data pertaining to factors that influence the environmental mediation of influenza transmission are critically reviewed, including: frequency, magnitude and size distribution and virus expiration, inactivation rates, environmental and self-contact rates, and viral transfer efficiencies during contacts. Where appropriate, two-stage Monte Carlo uncertainty analysis is used to characterize variability and uncertainty in the reported data. Significant uncertainties are present in most factors, due to: limitations in instrumentation or study realism; lack of docu

SUBMITTER: Jones RM 

PROVIDER: S-EPMC7169173 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature