High diagnostic accuracy of the Sysmex XT-2000iV delta total nucleated cells on effusions for feline infectious peritonitis.

ABSTRACT:

Background

The ΔWBC (the ratio between DIFF and BASO counts of the Sysmex XT-2000iV), hereafter defined as ΔTNC (total nucleated cells), is high in effusions due to feline infectious peritonitis (FIP), as cells are entrapped in fibrin clots formed in the BASO reagent. Similar clots form in the Rivalta's test, a method with high diagnostic accuracy for FIP.

Objectives

The objective of this study was to determine the diagnostic accuracy for FIP and the optimal cutoff of ΔTNC.

Methods

After a retrospective search of our database, DIFF and BASO counts, and the ΔTNC from cats with and without FIP were compared to each other. Sensitivity, specificity, and positive and negative likelihood ratios (LR+, LR-) were calculated. A ROC curve was designed to determine the cutoff for

SUBMITTER: Giordano A 

PROVIDER: S-EPMC7169253 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature