Maternal and paternal preconception exposure to phenols and preterm birth.

ABSTRACT:

Background

Phenol exposure during pregnancy has been associated with preterm birth, but the potential effect of preconception exposure in either parent is unknown. There is a growing body of evidence to suggest that the preconception period is a critical window of vulnerability for adverse pregnancy outcomes.

Objective

We examined whether maternal and paternal preconception urinary concentrations of select phenols were associated with the risk of preterm birth among couples attending fertility care.

Methods

The analysis included 417 female and 229 male participants of the Environment and Reproductive Health (EARTH) Study who gave birth to 418 singleton infants between 2005 and 2018 and for whom we had phenol biomarkers quantified in at least one urine sample collected

SUBMITTER: Mustieles V 

PROVIDER: S-EPMC7169435 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature