Changes in metabolic complications in patients with alcoholic fatty liver disease monitored over two decades: NAGALA study.

ABSTRACT:

Objective

The social conditions are changing in the world, which may contribute to the change in lifestyle, including alcohol consumption and dietary intake; however, changes in metabolic complications in patients with alcoholic fatty liver disease (AFLD) have never been reported. Therefore, here we compare the metabolic complications in current AFLD with those of two decades ago.

Methods

We performed this cross-sectional study in a Japanese health check-up centre. Consecutive participants who visited the facilities between June 1994 and December 1997 or between January 2014 and December 2017 were enrolled. A total of 7499 participants (4804 men, 2695 women) in the past cohort and 20 029 participants (11 676 men, 8353 women) in the current cohort were entered to this study.<

SUBMITTER: Hamaguchi M 

PROVIDER: S-EPMC7170409 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature