Ontology highlight
ABSTRACT:
SUBMITTER: Roumans KHM
PROVIDER: S-EPMC7170906 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Nature communications 20200420 1
Hepatic steatosis is associated with poor cardiometabolic health, with de novo lipogenesis (DNL) contributing to hepatic steatosis and subsequent insulin resistance. Hepatic saturated fatty acids (SFA) may be a marker of DNL and are suggested to be most detrimental in contributing to insulin resistance. Here, we show in a cross-sectional study design (ClinicalTrials.gov ID: NCT03211299) that we are able to distinguish the fractions of hepatic SFA, mono- and polyunsaturated fatty acids in healthy ...[more]