Withdrawal Symptoms From E-Cigarette Abstinence Among Former Smokers: A Pre-Post Clinical Trial.

ABSTRACT:

Introduction

The major aim of this study was to test whether abstinence from e-cigarettes causes withdrawal symptoms in former smokers.

Methods

We conducted an unblinded, within-participants, pre-post clinical trial in which 109 former smokers who were current daily electronic cigarette (e-cigarette) users used their own e-cigarette for 7 days followed by 6 days of biologically confirmed abstinence engendered via an escalating contingency payment system. Participants monitored symptoms of nicotine withdrawal daily via an Interactive Voice Response system. They also attended three laboratory visits per week for carbon monoxide and cotinine testing to verify abstinence.

Results

Half of participants completely abstained for a week. All the Diagnostic and Statistical Manu

SUBMITTER: Hughes JR 

PROVIDER: S-EPMC7171279 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature